Lung Recruitment During One Lung Ventilation

Effect of Stepwise Lung Recruitment Maneuver on Oxygenation, Lung Mechanics, Pulmonary Functions and Lung Injury Biomarkers During Lung Resection Surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202001518687696

Enrollment

Registered

2020-01-14

Start date

2019-12-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Respiratory Surgery Anaesthesia

Interventions

stepwise lung recruitment

Conventional volume controlled ventilation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 40 adult patients belonging to American Society of Anaesthesia (ASA) physical status class II – III with age ranged from 20-60 years scheduled for elective lung resection surgeries using one lung ventilation under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. New York Heart Association III to IV. 2. Arrhythmia with unstable haemodynamics. 3. Bronchopulmonary fistula. 4. Preoperative Hemoglobin < 10 gm/dl. 5. Previous contralateral lung resection surgery. 6. Predicted postoperative FEV1% (ppoFEV1 %) < 40% (which willaffect the decision of extubation).

Design outcomes

Primary

Measure	Time frame
Oxygenation parameters, Arterial blood gases, Oxygenation index, Alveolar arterial oxygen gradient.	—

Secondary

Measure	Time frame
• Lung mechanics. • Pulmonary functions. • Lung injury biomarker. • Haemodynamic parameters. • Need for postoperative mechanical ventilation. • Postoperative pulmonary complications.	—

Countries

Egypt

Contacts

Public ContactShahira Ahmed Yousef El Metainy

Professor of anesthesia and surgical icu

shelmetainy@yahoo.com01227498438

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026