Effects of Moderate Aerobic Exercise and Inspiratory Muscle Training on selected Clinical and Haematological Parameters Among Adults with Sickle Cell Disease

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202001495245937

Enrollment

120

Registered

2020-01-16

Start date

2022-01-03

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haematological Disorders

Interventions

Moderate aerobic exercise

Moderate aerobic exercise plus inspiratory muscle training

Medication only

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Diagnosis of Sickle Cell Disease type HbSS following electrophoresis test 2. Restricted pattern of spirometry. 3. Adults, aged 18 years and above who are able to perform pulmonary function test. 4. Patients who can understand instructions on how to carry out the procedure involved in this study 5. A non-smoker Sickle Cell Anaemia (SCA) patient. 6. Steady state patients that have not had crises for at least 1 month and no blood transfusion. 7. Individuals with no prior asthma history.

Exclusion criteria

Exclusion criteria: 1. Chronic lung diseases unrelated to sickle cell disease, such as COPD, asthma 2. Heart disease and pulmonary hypertension 3. Individuals with avascular necrosis 4. Individuals on hydroxyuria drug

Design outcomes

Primary

Measure	Time frame
Lung Function Test	—

Secondary

Measure	Time frame
Respiratory muscle strength, Functional capacity, Quality of life, respiratory symptoms, Full blood count and Lactate Dehydrogenase	—

Countries

Nigeria

Contacts

Public ContactAISHAT SHITTU

Lecturer Bayero University Kano

ashittu.pth@buk.edu.ng+2348036785233

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026