Rectal cancer
Conditions
Interventions
Laparoscopic Intersphincteric Resection With Total Mesorectal Excision for ultra Low Rectal Cancer
open surgical Intersphincteric Resection With Total Mesorectal Excision for ultra Low Rectal Cancer
Sponsors
Alexandria main university hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with low rectal carcinoma (The lowest margin of tumor located 3 cm from anal verge ; ¿ 2 cm from dentate lines; 1 cm from anorectal rings. Local spread restricted to the rectal wall or the internal anal sphincter. Adequate preoperative sphincter function and continence. Absence of distant metastasis.
Exclusion criteria
Exclusion criteria: Contraindications to major surgery and American Society of Anesthesiologists (ASA) Physical Status scoring 4. Metastatic rectal cancer. Those in Dukes stage D (T4 lesion). Undifferentiated tumours. Local infiltration of external anal sphincter or levator ani muscles. Tumor located more than 2 cm above the dentate line. Presence of fecal incontinence. Patients unwilling to take part in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospital stay | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of the intervention ;Amount of blood loss and rate of blood transfusion ;The onset of intestinal motility.;Pain score ;Postoperative complications ;30 days follow up for readmission in the postoperative period ;Clinical functional outcome of intersphincteric resection;Local recurrence within 2 years ;Distant metastasis within 2 years;conversion rate for laparoscopic ISR | — |
Countries
Egypt
Contacts
Public ContactIsraa aly
ethical committe director
Outcome results
None listed