Fertility-female
Conditions
Interventions
placebo group
study group
Sponsors
faculty of medicine suez canal university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Serum AMH <1.1 ng/ml 2. Serum FSH =10 mIU/L and =15 mIU/L on day 3 of cycle 3. Low antral follicle counts (AFC) = 4 on Day 3 of cycle
Exclusion criteria
Exclusion criteria: 1. Patients exposed to cytotoxic or radiotherapy for pelvic malignancies. 2. Patients on herbal or hormonal therapy. 3. Patients with cystectomy or oophorectomy. 4. Cases contraindicated to be supplemented with DHEA o Chronic kidney diseases, o Chronic liver diseases, o Diabetes, o Breast or Uterine cancers, o Endometriosis, o Fibroids, o Adrenal gland hyperplasia, o Psychological disorders like depression. 5. Hyperprolactinaemia. 6. Polycystic ovaries syndrome. 7. Severe male factor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of DHEA supplementation on ovarian reserve among females with poor ovarian reserve. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the outcomes of induction in both the study and the control groups, in which: 1. The number of mature follicles at time of ovulation. 2. The total dose of gonadotrophin stimulation needed for induction of ovulation. 3. The duration of ovarian stimulation. 4. E2 level at the day of hCG injection to assess the quantity and the quality of mature follicles. | — |
Countries
Egypt
Contacts
Public Contactomima taha
suez canal university
Outcome results
None listed