Analgesic efficacy of ultrasound guided bilateral transversus thoracis muscle plane block in pediatric cardiac surgery

Analgesic efficacy of ultrasound guided bilateral transversus thoracis muscle plane block in pediatric cardiac surgery: a prospective randomized study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR201910859535009

Enrollment

Registered

2019-10-16

Start date

2019-11-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatrics Anaesthesia

Interventions

Normal saline that will be injected into transversus thoracis muscle plane

transversus thoracis muscle plane block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 2 to 12 years. 2. Scheduled for elective cardiac surgery. 3. Via median sternotomy. 4. Congenital simple left to right intra cardiac shunt

Exclusion criteria

Exclusion criteria: 1. Refusal patients guardians. 2. Redo cardiac surgery. 3. Local infection of the skin and subcutaneous tissue at the site of needle puncture 4. Hypersensitivity to local anesthetics. 5. Coagulation disorders.

Design outcomes

Primary

Measure	Time frame
1- Total dose of intra operative fentanyl requirements. 2- Post operative pain that will be assessed at 1h, 2h, 6h, 12h, 18, 24 after extubation, and will be managed according to objective pain discomfort score(OPDS) in children.	—

Secondary

Measure	Time frame
1-Heart rate [HR] and invasive mean arterial blood pressure [MAP] will be recorded; before induction of anesthesia (basal value), after induction of anesthesia, after skin incision, after sternotomy, 15 min after CPB and after the closure of sternum. 2- Total dose of intra operative fentanyl requirements(ug/kg). 3- Aortic cross clamping time (minutes). 4- Cardiopulmonary bypass time (minutes). 5-The number of patients who will be extubated in operating room (within 15 minutes of the end of surgery) were recorded. 6- Time to extubation (hours). 7- Post extubation PaO2, PaCO2 will be assessed each 3 hour for 24 hours. 8-Time of first rescue analgesia 9- Total dose of morphine consumption in the first 24 postoperative hours. 10- Intensive care unit (ICU) length of stay. 11- Postoperative complications (the need for re-intubation, nausea and vomiting, pruritus, respiratory depression and neurological deficits) will be reported	—

Measure

Time frame

1-Heart rate [HR] and invasive mean arterial blood pressure [MAP] will be recorded; before induction of anesthesia (basal value), after induction of anesthesia, after skin incision, after sternotomy, 15 min after CPB and after the closure of sternum. 2- Total dose of intra operative fentanyl requirements(ug/kg). 3- Aortic cross clamping time (minutes). 4- Cardiopulmonary bypass time (minutes). 5-The number of patients who will be extubated in operating room (within 15 minutes of the end of surgery) were recorded. 6- Time to extubation (hours). 7- Post extubation PaO2, PaCO2 will be assessed each 3 hour for 24 hours. 8-Time of first rescue analgesia 9- Total dose of morphine consumption in the first 24 postoperative hours. 10- Intensive care unit (ICU) length of stay. 11- Postoperative complications (the need for re-intubation, nausea and vomiting, pruritus, respiratory depression and neurological deficits) will be reported

—

Countries

Egypt

Contacts

Public ContactNabil Abd Elraouf

Professor of anesthesia and surgical Intensive care

nabil_abdelraouf@yahoo.com+20100491538648

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026