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Diode Laser and Red Complex Periodontal Bacteria

Diode Laser as an Additional Therapeutic Measure in Reducing Red Complex Bacteria in Chronic Periodontitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR201909915338276
Enrollment
25
Registered
2019-09-05
Start date
2015-01-05
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Diode laser

Sponsors

Dr Sune Mulder van Staden
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The participants had to be adult patients (over the age of 18 years-64 years). For the purpose of this study the participants were diagnosed with chronic periodontitis and had to present with a minimum of four teeth present per quadrant. At least three teeth per quadrant had to present with periodontal probing pocket depths of 5mm or more in any of the six point probing areas namely mesio-buccal (MB), buccal (B), disto-buccal (DB), mesio-palatal (MP), palatal (P), disto-palatal (DP) per tooth were assessed. Clinical features defining a diagnosis of chronic periodontitis: Oedema and tissue erythema Moderate accumulations of plaque and calculus Bleeding on probing (BOP) Increased pocket depths (minimum probing pocket depth of 4mm) Radiographic evidence of bone loss (angular or horizontal) Tooth mobility Varying degrees of clinical attachment loss Slow to moderate rate of progression Amount of destruction consistent with the presence of local factors – such as plaque and calculus. The chronic periodontitis could have presented as localised (30% of sites affected). The severity of the chronic periodontitis could have presented as mild (CAL= 1-2mm), moderate (CAL=3-4mm) or severe (CAL > 5mm) (Lindhe, 2015:129). All the above mentioned variants of chronic periodontitis were included in this study.

Exclusion criteria

Exclusion criteria: Patients under 18 years and over 65 years. The only underlying medical conditions that were excluded were patients that were pregnant (or lactating) and patients undergoing radiation or chemotherapy. Patients with oral pigmentation of the attached gingiva in the study area of interest were also excluded from the study, as pigments (such as melanin) absorb laser energy at varying amounts which could potentially have an effect on the results. Patients who smoked more than 10 cigarettes per day were excluded.Patients that had taken antibiotics in the previous 6 months were excluded.Patients who had periodontal treatment in the previous 6 months were also excluded.

Design outcomes

Primary

MeasureTime frame
Bacterial determination and the change in the colony forming units.

Secondary

MeasureTime frame
All patients receive the diode laser after 6 weeks if the diode laser adjuct reduced the red complex bacteria colony forming units.

Countries

South Africa

Contacts

Public ContactSune Mulder van Staden

Consultant

drsunemulder@gmail.com+279373107

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 24, 2026