Fertility-female
Conditions
Interventions
cold drilling and letrozole group
Sponsors
faculty of medicine suez canal university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Women in reproductive age (18-45 years ) 2) All participants fulfilled the diagnosis for PCOS, two of the following three criteria: A) Chronic anovulation. B) Hyperandrogenism (clinical/biologic). C) Polycystic ovaries on transvaginal ultrasound scan , ovarian enlargement and at least one ovary with 10–30 subcapsular follicles of 3–8 mm in diameter were present in each case. 3) All patients are clomiphene citrate resistant; means that women were previously treated with clomiphene citrate 100mg daily for 5 days per cycle, for 2–3 cycles, with persistent anovulation or ovulation with very thin endometrium, <5 mm at the time of HCG adminstiration. 4) All patients have normal TSH and prolactin level
Exclusion criteria
Exclusion criteria: 1. Previous history of ovarian drilling 2. previous treatment with metformin 3. patients with an abnormal hysterosalpingogram 4. previous pelvic operations 5. preexisting ovarian cyst on day three of the cycle 6. patient with husband has abnormal semen parameters
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of Ultrasound-guided transvaginal ovarian needle puncture on polycystic ovary syndrome women who are resistant to clomiphene citrate. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess Ultrasound-guided transvaginal ovarian needle puncture effect on the on hormonal profile, ovulation rates and the improvement of symptoms on polycystic ovary syndrome women. | — |
Countries
Egypt
Contacts
Public Contactomima taha
suez canal university
Outcome results
None listed