Effect of vitamin D on renin angiotensin system in heart failure patients

Effect of vitamin D on renin angiotensin system in heart failure patients with reduced ejection fraction

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR201908774181973

Enrollment

Registered

2019-08-26

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System

Interventions

vitamin D

control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: adults > 18 years heart failure with left ventricular ejection fraction == 90 mmhg) blood concentration of vitamin D =< 50 nmol/l

Exclusion criteria

Exclusion criteria: non inclusion criteria heart faiture decompensation and worsening clinical status, cardiogenic schock renal insufficiency with cockroft formula creatinin claerance = 2.6 mmol/l baseline blood concentration of vitamin D > 50nmol/l exclusion criteria calcemia > 2.6 mmol/l before the second administration of vitamin D blood concentration of vitamin D > 50nmol/l before the second administration of vitamin D

Design outcomes

Primary

Measure	Time frame
lowering of active renin plasma concentration	—

Secondary

Measure	Time frame
lowering of plasma level of brain natriuretic peptide (BNP)	—

Countries

Tunisia

Contacts

Public Contactfathia mghaieth zghal

MCA cardiology faculty of mecicine of tunis university tunis el manar cardiology department rabta hospital

fathia.zghal@fmt.utm.tn0021698648676

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026