endometrial hyperplasia
Conditions
Interventions
mirena group
Sponsors
faculty of medicine suez canal university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1- Women between the ages of 18-75 years old. 2- Women with a histological diagnosis of endometrial hyperplasia without atypia confirmed by endometrial biopsy.
Exclusion criteria
Exclusion criteria: 1- Pregnant women. 2- Women with contraindication to Metformin (Impaired renal functions , Cirrhosis of the liver, Hepatitis and Alcoholism). 3- Women with contraindications to Mirena (e.g. acute genital tract inflammatory disease, genital bleeding of unknown etiology, hypersensitivity to any component of this product, congenital or acquired uterine anomaly, known or suspected breast cancer, known or suspected uterine and cervical neoplasia or acute liver disease or liver tumor). 4- Women with concurrent endometrial cancer . 5- Women with a history of a hormone-dependent malignancy (e.g. breast cancer). 6- Women taking tamoxifen.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| evaluation of hyperplasia resolution by comparison of pre- and post-treatment endometrial biopsies. | — |
Secondary
| Measure | Time frame |
|---|---|
| intervention related side effects | — |
Countries
Egypt
Contacts
Public Contactomima taha
suez canal university
Outcome results
None listed