Nervous System Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: -Patients presenting by their first ischemic or hemorrhagic cerebrovascular stroke within >two weeks from onset so patients could have passed the flaccid stage and < six months duration of symptoms, as the best cortical plasticity is obtained in a period less than six months(Takeuchi et al., 2009). -Subcortical hemispheric stroke confirmed by magnetic resonance imaging (MRI). -Patients of a minor (1-4) to moderate (5-15) national institutes of health stroke scale score (Lyden, Lu & Levine, 2001) to allow patient to receive treatment and perform tests (Wolf Motor function test and Fugl Meyer assessment) to assess improvement with minimum assistance. -No prior experience of rTMS to confirm blindness of the intervention
Exclusion criteria
Exclusion criteria: -Family history of epilepsy or patients who are known to be epileptic. -Pregnant females. -Convulsion after the stroke onset -Patients with any medical metal devices incompatible with transcranial magnetic stimulation (pacemaker). -Bi-hemispheric or multifocal stroke. -Premorbid lower motor neuron impairment prior to the onset of stroke like peripheral neuropathy or radiculopathy.Other comorbidities as fracture or deformity. -Patients with heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assesment Of bilateral rtms therapy (Stimulatory 5Hz rTMS over the affected hemisphere alternated by inhibitory 1Hz rTMS over the non-affected hemisphere) could lead to an improvement in the motor function of the paretic hand in stroke patients | — |
Secondary
| Measure | Time frame |
|---|---|
| improvement of post stroke spascity if present | — |
Countries
Egypt
Contacts
professor of internal medicine cairo university kasr alainy hospitals