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Opioid Free versus Opioid Based Anaesthesia on Breast Cancer Pain Score and Immune Response

The Effect of Opioid Free Versus Opioid Based Anaesthesia on Breast Cancer Pain Score and Immune Response

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201907659337128
Enrollment
40
Registered
2019-07-12
Start date
2019-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Anaesthesia

Interventions

Opioid free anaesthesia group
Opioid based anaesthesia group

Sponsors

Department of Anesthesia and Pain Management Medical Research Institute Alexandria University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: American Society of Anesthesiology (ASA) physical status class I and II.

Exclusion criteria

Exclusion criteria: Patient refusal Gastroesophageal reflux disease and history of peptic ulcer. Renal or hepatic impairment. Reconstructive breast surgery, re-do surgery or previous mastectomy of the other breast. Coagulopthies Body Mass Index > 35 kg/m2. Immunosuppressive therapy and immune disorders. Metastasis, radiotherapy or chemotherapy before surgery. Pregnancy. Patients with a psychiatric disorder. History of allergy to local anaesthetics.

Design outcomes

Primary

MeasureTime frame
Pain intensity using the Visual Analogue Scale (VAS) in the first 24 hours postoperatively. ;Screening for post-mastectomy neuropathic pain.—

Secondary

MeasureTime frame
Effect of opioid and surgical stress on the immune system.—

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026