The effect of Sildenafil on the success rate of ovulation induction with Clomiphene citrate versusClomiphene Citrate alone in unexplained infertility patients

Sildenafil together with clomiphene citrate to improve success rate of ovulation induction in unexplained infertility patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201907658492123

Enrollment

Registered

2019-07-24

Start date

2018-06-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female

Interventions

placebo

clomiphene citrate and sildenafil

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: infertile women whether it was primary or secondary, women's age: (18-40 years old), menstrual cycle from (24-35 days) normal recent semen analysis of the husband within last 6 months.

Exclusion criteria

Exclusion criteria: presence of ovarian cysts, abnormal hormonal profile, significant cardiovascular disease, serious liver disease or renal failure history of pelvic pathology "pelvic adhesions".

Design outcomes

Primary

Measure	Time frame
To assess the success of sildenafil plus clomiphene citrate versus clomiphene citrate alone for induction of ovulation in unexplained infertility patients.	—

Secondary

Measure	Time frame
To assess the effects of sildenafil on pregnancy rate, endometrial thickness, follicular development, and side effects after ovulation induction cycles with clomiphene citrate.	—

Countries

Egypt

Contacts

Public Contactomima taha

lecturer

omimatharwat@yahoo.com0020123423685

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026