A randomized controlled double-blind study comparing dexmedetomidine and esmolol effects on Cardiac recovery in patients undergoing valve replacement surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201902822178026

Enrollment

120

Registered

2019-02-18

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System Cardiology Anaesthesia

Interventions

dexmedetomidine

esmolol

normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients aged 18-70 years old, ASA I-III, of both sexes undergoing valve replacement surgery

Exclusion criteria

Exclusion criteria: Patients refused to take part in the study, allergic to esmolol and dexmedetomidine, asthmatic, history of ß-blocker or dexmedetomidine intake, history of cardiac conduction abnormalities and with pericarditis

Design outcomes

Primary

Measure	Time frame
the recovery time (time from reperfusion to steady heart rate)	—

Secondary

Measure	Time frame
ventricular fibrillation ;atrial fibrillation	—

Countries

Egypt

Contacts

Public Contactahmed metwally

professor of anesthesia

drahmedabdelraoufmetwally@yahoo.com00201227968325

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026