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Evaluation of The Regenerative Potential of a Novel Treated Dentin Matrix Hydrogel and Bioactive Dentin Substitute in Direct Pulp Capping

Clinical And Histological Evaluation of The Regenerative Potential of a Novel Treated Dentin Matrix Hydrogel and Bioactive Dentin Substitute in Direct Pulp Capping (A Randomized Controlled Trial)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201901866476410
Enrollment
45
Registered
2019-01-30
Start date
2019-02-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Treated dentin matrix hydrogel TDMH
Biodentine

Sponsors

Department of Conservative Dentistry Faculty of Dentistry Alexandria University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Clinically diagnosed carious permanent posterior teeth with accidental traumatic pulp exposures and without any periapical pathology. - Exposures with controllable light red bleeding and within an estimated size of 1 mm2 will be considered. - No history of spontaneous pain in response to temperature or biting. - Soft tissues around the tooth are normal. - The patient with good oral hygiene. - The patient has non-contributory medical history. - The treated teeth will not be used as abutments for fixed or removable partial dentures.

Exclusion criteria

Exclusion criteria: - Teeth with pathological exposures. - Teeth with exposures with excessive uncontrollable bleeding. - Non-restorable tooth. - Teeth having subgingival margins. - Teeth that have not erupted sufficiently to allow isolation with rubber dam. - Teeth with pathological mobility. - Swelling of associated tissues.

Design outcomes

Primary

MeasureTime frame
Clinical and radiographic success of direct pulp capping procedure done in traumatically exposed permanent posteriduring cavity preparation using TDMH, Biodentine and MTA

Secondary

MeasureTime frame
Histological evaluation of pulpal response after direct pulp capping procedure in premolars scheduled to be extracted for orthodontic reasons using TDMH, Biodentine and MTA.

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026