Training caregivers to enhance early child neurodevelopment in the prevention of konzo disease from toxic cassava in the Democratic Republic of Congo

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR201901631942297

Enrollment

400

Registered

2019-01-24

Start date

2018-06-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders Nervous System Diseases

Interventions

Wetting method and Mediational Intervention for Sensitizing Children

Wetting method

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All mother-child dyads with children aged 0-5 years Dyads living in Kahemba (study site) Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Children with infectious or somatic conditions that can affect early child cognitive development Children with other neurological conditions that can affect early child cognitive development

Design outcomes

Primary

Measure	Time frame
The primary outcome will be changes in cassava cyanogenic content by the trainees and Urine thiocyanate level in the children in their MISC/WTM versus WTM only intervention households and enhance early child development and neurocognition of children in the 200 included households.	—

Secondary

Measure	Time frame
Neurodevelopmental and cognitive performance scores in the children using selected tools for neurocognitive assessments	—

Countries

Democratic Republic of the Congo

Contacts

Public ContactEsperance Kashala Abotnes

INRB

esperance_kashala@yahoo.com+41003043

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026