Selenium as a sole treatment for Oral Lichen Planus

Effect of Selenium in the Treatment of Oral Erosive Lichen Planus Based on Salivary Oxidative Markers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201901531815403

Enrollment

Registered

2019-01-23

Start date

2017-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Topical Selenium

Systemic Selenium

Topical corticosteroid Triamcinolone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosis of oral erosive LP was based on clinical manifestations and confirmed by incisional biopsy according to the modified WHO criterial 2003. Patient’s age range between 30-60 years old. Both males and females will be included in the study

Exclusion criteria

Exclusion criteria: Smoking and tobacco use in any form. Pregnant and lactating females. Patients with suspected restoration or drug-related reaction (Lichenoid contact/drug reaction). Patients with any systemic disease (diabetes, live disease, renal disease. Ect.) Patients with cutaneous Lichen planus (skin lesions associating OLP) or any other extraoral-mucosal site. Patients with history of cancer

Design outcomes

Primary

Measure	Time frame
Salivary Malondialdehyde level;Salivary Total antioxidant capacity level	—

Secondary

Measure	Time frame
Clinical lesion size score using Thongprasom et. Al., scoring system. ;Pain score using Numerical rating score (NRS)	—

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026