Uterine Fibroids
Conditions
Interventions
Group I
Placebo
Sponsors
DR. AMADU MOTUNRAYO BUKOLA
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Subjects were consenting non-pregnant women with a diagnosis of symptomatic fibroid scheduled for abdominal myomectomy. 2. Uterine size less than or equal to 28 weeks. 3. Women without pre-operative Anemia (i.e Haemoglobin concentration =10g/dl)
Exclusion criteria
Exclusion criteria: 1. Women with pre-operative Anemia (i.e Haemoglobin concentration <10g/dl). 2. Uterine size greater than 28 weeks. 3. Patients concurrently on medications such as gonadotropin releasing hormone analogues, mefenamic acid and other hormones. 4. Patients with previous abdominal surgery. 5. Cases where haemostatic tourniquet use is impossible. 6. Chronic liver diseases, nephropathies, bleeding disorders and past thromboembolic disorders. 7. Known hypersensitivity to Tranexamic Acid. 8. Pregnancy . 9. Refusal of patient to consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Amount of perioperative blood loss using combination of gravimetric method and amount of blood in suctioning machine at the end of surgery. 2)Twenty-four hours post-operative hemoglobin and hematocrit values were obtained. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Changes in vital signs (pulse rate, blood pressure, respiratory rate). 2) Need for other surgical measures to stop bleeding such as uterine artery ligation, hysterectomy. 3) Need for intraoperative blood transfusion. 4) Need for use of other anti-haemorrhagic agents. | — |
Countries
Nigeria
Contacts
Public ContactJIMOH ABDULGAFAR
HOD
Outcome results
None listed