Skip to content

Mobile phone SMS for adherence support for hypertension in South African adults in care for HIV infection

MObile Phone text messages to support Hypertension treatment ADherence in adults attending HIV treatment centres in the Western Cape Province of South Africa: a pilot study – The MOPHADHIV trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201811878799717
Enrollment
700
Registered
2018-11-20
Start date
2019-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System HIV/AIDS

Interventions

SMS adherence support
Usual care

Sponsors

South African Medical Research Council
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients will be included if the following are satisfied: A) Diagnosed with HIV and Hypertension; B) on ART and on blood pressure lowering medication (or about to start); C) BP at recruitment >140/90 mmHg; D) within 8 weeks of a viral load test (to offset the cost of baseline viral load and reduce the overall cost of the study); E) accessing care for both HIV and hypertension at selected sites; F) have regular access to a mobile phone and able to access SMS text messages; G) >18 years of age and willing to participate and give written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria: A) requirering specialist care for hypertension; B) self-reported pregnancy or within three months post-partum; C) very high BP (systolic >220 mmHg or diastolic >120 mmHg) or symptoms suggestion hypertensive emergency; D) Active malignancy or ongoing treatment for malignancy; E) Acutely unwell patients.

Design outcomes

Primary

MeasureTime frame
Mean difference in systolic and diastolic blood Pressure

Secondary

MeasureTime frame
1) uptake and adherence to BP medications, 2) uptake an adherence to HIV specific medications, 3) mean change in lipid variables, 4) mean change in CD4 count and viral load, 4) mean change in adiposity variables, 5) change in kidney function; Tertiary - 1) Descriptive analysis of the process involved in the intervention, 2) Economic analysis, 3) Quality of life.

Countries

South Africa

Contacts

Public ContactKim Ahn Nguyen

Scientist SAMRC

Kim.Nguyen@mrc.ac.za0027219380422

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026