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Site-oriented depigmentation in vitiligo patients using Q-switched Nd:YAG laser (1064/532nm), cryotherapy and chemical peels: A comparative study.

Site-oriented depigmentation in vitiligo patients using Q-switched Nd:YAG laser (1064/532nm), cryotherapy and chemical peels: A comparative study.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR201811835577312
Enrollment
80
Registered
2018-11-30
Start date
2016-02-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin and Connective Tissue Diseases

Interventions

Chemical peels and laser
Cryotherapy chemical peel and laser
no intervention

Sponsors

Sarah Ibrahim
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients older than 12 years having either vitiligo universalis that left behind residual normally pigmented and cosmetically unacceptable areas over face, neck and/or upper limbs, or vitiligo vulgaris recalcitrant to treatment and interfering with patients’ social acceptance were included.

Exclusion criteria

Exclusion criteria: ? Active cutaneous infection or inflammatory dermatoses. ? Uncooperative patients. ? Unrealistic expectations. ? History of abnormal scarring. ? Patients having cardiac or renal problems. ? Patients with impaired sensation or circulation, or abnormal reactions to cold (Raynaud's phenomenon and cold urticaria).

Design outcomes

Primary

MeasureTime frame
The used depigmenting modalities proved to be effective in depigmentation of the remaining pigmented areas in vitiligo cases

Secondary

MeasureTime frame
TCA peels are tolerable, cheap and available depigmenting agents in face and/ or neck depigmentation. QsNdYAG, cyotherapy and phenol 88 gave comparable results in upper limb depigmentation.

Countries

Egypt

Contacts

Public ContactSarah Ismail

Lecturer of Dermatology Cairo University.

sarah.ibrahim@kasralainy.edu.eg+201224247232

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026