HIV/AIDS Paediatrics Cardiology
Conditions
Interventions
Niacin
Placebo
Statin
Sponsors
Prof Siyazi Mda
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All children who have been on ART for at least 6 months, who are attending the HIV clinic at DGMAH POPD and whose caregivers give consent, will be screened for dyslipidaemia. Those who test positive for dyslipidaemia will be enrolled (after obtaining informed consent) into the study. Non-probability convenience sampling will be used.
Exclusion criteria
Exclusion criteria: Children with an underlying disease that predisposes them to hyperlipidaemia (e.g. diabetes mellitus, nephrotic syndrome, chronic liver disease, familial hypercholesterolemia and hypothyroidism) will be excluded. Poor adherence to ART (high pill count on hospital visits, current investigation for resistance testing, poor viral suppression), and those who are already on lipid lowering agents will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant change in blood lipid values as categorised by the National Cholesterol Education Program (NCEP) Adult Treatment Panel III; American Academy of Pediatrics (NCEP ATP III / AAP). | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometrical measures of physical growth. Weight, height, mid-upper arm circumference, waist circumference, hip circumference. ;Liver function tests and glucose test | — |
Countries
South Africa
Contacts
Public ContactEstelle Viljoen
Lecturer SMU Department of Human Nutrition and Dietetics
Outcome results
None listed