Skin and Connective Tissue Diseases
Conditions
Interventions
Sponsors
Cairo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with mild to moderate atopic dermatitis, defined according to Hanifin and Rajka criteria by the presence of 3 major and 3 minor criteria, and by scoring less than 50 points in SCORAD. Both genders. Age more than 6 years old, as children less than 6 are not allowed to be treated by whole cabinet NB-UVB as per phototherapy unit regulations.
Exclusion criteria
Exclusion criteria: Severe AD: SCORAD>50 (Oranje, 2011). Erythrodermic patients and those indicated for more aggressive systemic immune suppressive therapy. Patients receiving systemic treatment within one month or topical treatment within 2 weeks before enrollment into the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical effectiveness as assessed by reduction of SCORAD and/or of pruritus by at least 50%(SCORAD50 and ITCH50 respectively).;Reduction of staphylococcal load on the skin of treated patients, as assessed quantitatively by log Colony Forming Units (CFU).;Impact of staphylococcal colonization and initial severity on treatment response. | — |
Secondary
| Measure | Time frame |
|---|---|
| Prevention of flares or exacerbations that need topical or systemic therapy in the 4 week follow-up period after cessation of treatment. | — |
Countries
Egypt
Contacts
Public ContactAhmed Mourad
Resident of dermatology Kasr AlAiny Hospital
Outcome results
None listed