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Albuterol as an Adjuvant Therapy in Acute Anticholinesterase Pesticides Poisoning: A Randomized Clinical Trial

Albuterol as an Adjuvant Therapy in Acute Anticholinesterase Pesticides Poisoning: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR201810624534118
Enrollment
60
Registered
2018-10-03
Start date
2017-05-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning

Interventions

nebulized albuterol
normal saline by nebulization

Sponsors

Tanta university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Acute anticholinesterase poisoned patients symptomatic patients

Exclusion criteria

Exclusion criteria: Patients less than 12 years of age Pregnant and lactating women Patients with ingestion or exposure to other substances in addition to the anticholinesterase pesticide Patients with other major medical conditions (e.g. respiratory or cardiovascular disease, renal or hepatic failure) Patients presenting more than 12 hours of having consumed the pesticide (late presenters) Patients receiving unreported treatments

Design outcomes

Primary

MeasureTime frame
change in oxygenation as measured by improvement of oxygen saturation from the base line to normal level within 60 minutes

Secondary

MeasureTime frame
Heart rate, respiratory rate and Blood pressure;Requirement of total atropine dose after adding nebulized albuterol ; Need for mechanical ventilation, mortality percentage, period of hospital stay.

Countries

Egypt

Contacts

Public ContactAl shaimma El mansy

Assistant Lecturer

alshaimmaelmansy@gmail.com00201067702858

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026