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Determining the minimum dose required of Remifentanil to obtain adequate intubating conditions in children presenting for day case surgery - a randomised controlled trial

Determining the minimum dose required of Remifentanil to obtain adequate intubating conditions in children presenting for day case surgery - a randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201809879218534
Enrollment
60
Registered
2018-09-25
Start date
2018-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Remifentanil

Sponsors

University of Pretoria Faculty of Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria include: Patients aged three to ten years of age, Elective dental/maxillofascial surgery, ASA 1 and 2 patients, Patients fasted according to current guidelines (Milk and solid food is six hours; breastmilk is four hours; clear fluids is two hours)

Exclusion criteria

Exclusion criteria: Exclusion criteria is as follows: Parental/guardian refusal Patient refusal, If the patient is allergic to any of agents used in this study, Patient not in specified age group, Bacterial or viral upper/lower respiratory tract infection, Difficult airway, Patients known with or a family history of anaesthetic complications such as porphyria or malignant hyperthermia, Patients known with obstructive sleep apnoea or at risk of developing obstructive sleep apnoea, Patients with heart murmurs that have not yet been investigated and diagnosed, Patients with congenital heart disease, Any patient at risk of aspiration (due to not being starved or due to a medical condition such as diabetes mellitus)

Design outcomes

Primary

MeasureTime frame
To determine the minimum required dose of remifentanil needed for intubation in children presenting for day case surgery without the use of neuromuscular blocking agent

Secondary

MeasureTime frame
To determine the dose of remifentanil for effective intubation with the least haemodynamic interference.

Countries

South Africa

Contacts

Public ContactKaren Van der Stockt

Registrar in Anaesthesia at the University of Pretoria

karenvdsice@gmail.com+27722625032

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026