Biological Performance of Custom CAD /CAM Abutments for Single Dental Implants Restoring Mandibular First Molars: RCT

Biological Performance of Custom CAD /CAM Abutments for Single Dental Implants Restoring Mandibular First Molars (A Randomized Controlled Trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201809736563842

Enrollment

Registered

2018-09-25

Start date

2018-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Custom CAD CAM

Premachined stock titanium

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a missing mandibular first molar, with natural tooth antagonist. Good oral hygiene with attitude for compliance to perform strict oral hygiene measures (Plaque index score = 0-1). Adequate bone quantity and quality for placement of dental implants.

Exclusion criteria

Exclusion criteria: Systemic or local diseases that might contraindicate surgical implant placement, or interfere with proper osseointegration. Parafunctional habits or any sign and symptom of pathological occlusion. Smoking. Pregnancy

Design outcomes

Primary

Measure	Time frame
MMP-8 level in peri-implant sulcular fluid around custom titanium CAD CAM and pre-machined stock titanium dental implant abutments.	—

Secondary

Measure	Time frame
Evaluation of periodontal clinical parameters (Plaque Index, Gingival Index, and Probing Depth) of soft tissues around both types of abutments. ;Assessment of crestal bone level through digital bitewing radiographs. ;Assessment of mechanical complications related to abutment screw or the crown restoration.	—

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient Information Manager

elsayedamr@yahoo.com00201223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026