Effect of Reciprocating Single-file and Rotary Instrumentation on the Intensity of Post-operative Pain and Amount of Endotoxins in Primarily Infected Root Canals

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR201808614861015

Enrollment

Registered

2018-08-31

Start date

2018-07-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Rotary Instrumentation

Reciprocating instrumentation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- Age between 13-73 years old. 2- Males or Females. 3- Permanent mandibular molar teeth with: * Non-vital response of pulp tissue. * Absence of spontaneous pain. * Pain on palpation or tenderness to percussion. * Periapical radiolucency or widening of periodontal membrane space.

Exclusion criteria

Exclusion criteria: 1- Patients who have: * Received antibiotic treatment during the last 3 months. * General diseases. 2- Teeth that have: * Periodontal pockets deeper than 4 mm. * Previous endodontic treatment

Design outcomes

Primary

Measure	Time frame
postoperative pain	—

Secondary

Measure	Time frame
quantification of endotoxins	—

Countries

Egypt

Contacts

Public ContactGeraldine Nasr

Associate Professor

geraldine.ahmed@dentistry.cu.edu.eg00201226322227

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026