Circulatory System HIV/AIDS Nutritional, Metabolic, Endocrine Cardiology
Conditions
Interventions
Behavioural and medical treatment of identifiable risk factors for cardiovascular disease
Sponsors
UKZN DRILL NIH Fogarty International Centre D43 grant
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: • HIV infected women • On ART for at least 1 year • Equal to/older than 18 years of age • Equal to/younger than 49 years of age • Plans to remain in the study catchment area for at least 3 years
Exclusion criteria
Exclusion criteria: • Participant declines study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of Women in the Intervention group with Post-intervention Modification of risk factors: Obesity (BMI, Waist circumference), Dyslipidaemia (Fasting lipid profile), Hypertension (Systolic BP), Diabetes (glycosuria, fasting glucose), Microalbuminuria (urine albumin), Elevated hsCRP. Presence of atherosclerosis detected by carotid intima media thickness. | — |
Secondary
| Measure | Time frame |
|---|---|
| Calculated cardiovascular risk as per WHO –ISH, DAD and Framingham compared to short term outcomes (presence of subclinical atherosclerosis by means of CMIT, presence of stroke, MI, angina -ischaemic heart disease) | — |
Countries
South Africa
Contacts
Public ContactSherika Hanley
Principal Investigator DRILL fellow
Outcome results
None listed