Patient-centred lifestyle rehabilitation for non-communicable disease in a low-resource setting

Patient-centred lifestyle rehabilitation for non-communicable disease in a low-resource setting: a feasibility and proof-of-concept randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201807847711940

Enrollment

200

Registered

2018-07-10

Start date

2018-09-17

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Circulatory System Nutritional, Metabolic, Endocrine Respiratory Cardiology

Interventions

Patient-centred Lifestyle Rehabilitation

Usual Care

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. At least 18 years of age or older (i.e. adult) 2. Able to perform in some weight-bearing or non-weight-bearing exercise 3. Minimal of one confirmed diagnosis according to the WHO classification of: cardiovascular disease (ICD: I0-99), chronic respiratory disease (ICD:J30-98), Malignant neoplasms (ICD: C00-97), or diabetes (E10-E14; excluding those with complications [minus E10.2-E10.29, E11.2-E11.29, E12.2, E13.2- E13.29, E14.2])

Exclusion criteria

Exclusion criteria: 1. No generic contraindications for exercise training or disease-specific contraindications for exercise training (according to American College of Sports Medicine guidelines) 2. Other contraindications for exercise prescription as determined by the medical practitioner. 3. Structured exercise training at regular intervals (more than once per week) at a moderate-to-vigorous intensity in the previous 3 months. 4. Psychiatric, substance abuse or known history of violence that would jeopardize the safe conduct of this program. 5. Pregnancy

Design outcomes

Primary

Measure	Time frame
Feasibility outcomes (eligible patients, participant and retention rate, group-allocation ratio, drop-out rate, and treatment adherence)	—

Secondary

Measure	Time frame
Physical examination (e.g. BMI, Blood Pressure, Lung Spirometry);Lifestyle risk factors (e.g. Smoking, Alcohol abuse);6-Minute Walk Test (6MWT);Pittsburg Quality of Sleep index;International Physical Activity Questionnaire;EQ-5D-5L ;Timed Up & Go test;Six-Spot-Step test;Patient-perspective cost-benefits (includes transportation costs, productivity cost questionnaire, direct medical costs);Treatment adherence;Treatment Fidelity	—

Measure

Time frame

Physical examination (e.g. BMI, Blood Pressure, Lung Spirometry);Lifestyle risk factors (e.g. Smoking, Alcohol abuse);6-Minute Walk Test (6MWT);Pittsburg Quality of Sleep index;International Physical Activity Questionnaire;EQ-5D-5L ;Timed Up & Go test;Six-Spot-Step test;Patient-perspective cost-benefits (includes transportation costs, productivity cost questionnaire, direct medical costs);Treatment adherence;Treatment Fidelity

—

Countries

South Africa

Contacts

Public ContactMartin Heine

AXA post doctoral research fellow

mheine@sun.ac.za+27760768342

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026