Ventilation strategy of ARDS management

Driving Pressure Guided Ventilation versus Protective Lung Ventilation in Acute Respiratory Distress Syndrome (ARDS) Patients: Prospective Randomized Controlled Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201807132391075

Enrollment

110

Registered

2018-07-16

Start date

2018-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory

Interventions

Control Group

Driving pressure guided PEEP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 18 years or older and fulfill the Berlin definition of ARDS (5) will be included: ? Acute onset within one week ? (PaO2/FiO2) less than 300 mmHg with a minimum PEEP of 5 cmH2O ? Bilateral lung opacities consistent with pulmonary edema on chest radiogram or lung ultrasound ? Cardiac failure and fluid overload should be excluded in absence of definite cause of ARDS

Exclusion criteria

Exclusion criteria: Patients aged 18 years or older and fulfill the Berlin definition of ARDS (5) will be included: ? Acute onset within one week ? (PaO2/FiO2) less than 300 mmHg with a minimum PEEP of 5 cmH2O ? Bilateral lung opacities consistent with pulmonary edema on chest radiogram or lung ultrasound ? Cardiac failure and fluid overload should be excluded in absence of definite cause of ARDS

Design outcomes

Primary

Measure	Time frame
28th day mortality	—

Secondary

Measure	Time frame
Oxygenation by PaO2 / FiO2;Lung compliance.	—

Countries

Egypt

Contacts

Public ContactFatheya Khalil

Head of Operating Room of Magrabi eye hospital for eyes Tanta

Fatheya.khalil@magrabi.com00201221218694

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026