HIV/AIDS Mental and Behavioural Disorders Nervous System Diseases HIV-associated neurocognitive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - 12-19-year-old male and female adolescents with chronic diseases (both HIV-positive and HIV-negative participants will be included to protect the HIV status) attending the clinic. - Participant is willing and able to give informed consent (for those aged 18 or 19 years old) or assent (for those aged 12 to 17 years old). - The primary caregiver is willing to give informed consent for participation in the study on behalf of participants aged 12 to 17 years old. - Participant¿s HIV status is known. - Participant is willing to share his/her HIV status with the study team. - Participant knows his/her own HIV status. - The participant must currently live in the MRC/Wits Agincourt Research Site villages and plan to remain in the study area for the next 6 months.
Exclusion criteria
Exclusion criteria: - profound hearing loss or deafness - current severe infective illness - another uncontrolled medical condition - cerebral palsy - known intellectual disability due to another cause - epilepsy - recent central nervous system infections - current or previous brain malignancies - a previous stroke - history of a significant head injury - current participation in a band or music group that involves the playing of musical instruments by the participant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The attendance rates, attrition rates and number of logistical problems encountered during implementation will be used to assess the feasibility of the programme.;The acceptability ratings from the early drop-out and endline acceptability questionnaires will be used as the outcome measure for acceptability of the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| OCS-Exec executive function test scores;OCS-Exec Iowa Gambling Task;Strengths and Difficulties Questionnaire emotional symptoms score;Strengths and Difficulties Questionnaire hyperactivity/inattention score;Strengths and Difficulties Questionnaire total difficulties score;Strengths and Difficulties Questionnaire prosocial behaviour score;Self-reporting questionnaire-20 (SRQ-20) score | — |
Countries
South Africa
Contacts
DPhil Student, Department of Psychiatry, University of Oxford