Musculoskeletal Diseases Osteoarthritis
Conditions
Sponsors
Faculty of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -symptomatic and radiographic diagnostic criteria of early knee OA -age 45-55 years -Body mass index less than 30.
Exclusion criteria
Exclusion criteria: -Patients with causes of secondary KOA (e.g. rheumatoid, gouty, traumatic soft tissues and bony injuries, mechanical malalignment with varus > 10 degrees and valgus > 15 after obtaining full limb radiograghs, etc.) -a history of knee surgery -intra-articular injection -use of antiresorptive drugs within the 12 months preceding enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The outcome instrument for evaluation of treatment regimen efficacy on symptoms of OA was the Western Ontario and McMaster Universities (WOMAC) OA index ;The visual analog scale (VAS) ;Radiographical evaluation included 1.5 T MRI ;measurement of urinary levels of the N-terminal crosslinking telopeptide of type I collagen ;measurement of urinary levels of C-terminal crosslinking telopeptide of type II collagen | — |
Secondary
| Measure | Time frame |
|---|---|
| Return to level of activity that was prior to symptoms of disease (Osteoarthritis). | — |
Countries
Egypt
Contacts
Public ContactElsayed Morsi
Professor of Orthopedic Surgery, Faculty of Medicine, Menoufia University
Outcome results
None listed