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Topical methotrexate-loaded nanoparticles for the treatment of vitiligo:a clinical trial

Topical methotrexate-loaded nanoparticles for the treatment of vitiligo:a clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201804003289316
Enrollment
60
Registered
2018-04-03
Start date
2018-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin and Connective Tissue Diseases vitiligo

Interventions

methotrexate treated group
placebo treated patients

Sponsors

alazhar university ,faculty of medicine for girls
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Vitiligo patients who don't use any systemic or local medication for at least one month prior to the onset of the study. -Age more than 18 years -both males and females

Exclusion criteria

Exclusion criteria: -Patients have systemic diseases(e.g. pulmonary diseases, hepatic diseases, neutropenia,anemia,pancytopenia) -Patients have a history or an active infection with Hepatitis C. -Pregnant and lactating females -Patients with age less than 18 -Patients suffering from any dermatological disease other than vitiligo.

Design outcomes

Primary

MeasureTime frame
-To evaluate the safety and efficacy of methotrexate loaded nano biopolymer as atopical treatment for vitiligo.

Secondary

MeasureTime frame
To assess the possibility of methotrexate loaded nano biopolymer to be an alternative for conventional vitiligo treatments.

Countries

Egypt

Contacts

Public ContactRana Mohamed Tarek Mohamed Fathy Gheith

dermatologist

ranagheith@hotmail.com00201005070206

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026