Proper premedication may alleviate or prevent the development of emergence agitation

Emergence Agitation after Pediatric Sevoflurane Anesthesia: A Placebo-controlled study for evaluation of prophylactic effect of oral premedication

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201804003286743

Enrollment

200

Registered

2018-04-03

Start date

2018-04-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders Evaluation of the ameliorative effect of premedication using oral midazolam, clonidine or gabapentine on the incidence of emergence agitation during recovery from sevoflurane anesthesia. Anaesthesia

Interventions

Group I

group II

group III

Group IV

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: children scheduled for elective outpatient pediatric surgeries as adeniodectomy,tonsillectomy, cleft clip,cleft palate and squint

Exclusion criteria

Exclusion criteria: allergy to any medication used,patients with upper respiratory infection and patients with ASA III and IV

Design outcomes

Primary

Measure	Time frame
the incidence of emergence agitation as evaluated by using the pediatric anesthesia emergence delirium scale and the four-point agitation scale.	—

Secondary

Measure	Time frame
time to emergence, defined as the time from sevoflurane discontinuation to the time to extubation.	—

Countries

Egypt

Contacts

Public Contactsherif arafa

lecturer of anesthesia , icu .aswan university

sherifarafa1020@gmail.com01005714014

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026