Combined Vs Sequential ICRS and CXL

Comparison Between Combined versus Sequential Intrastromal Corneal Ring Segments and Corneal Collagen Cross-linking for Treatment of Keratoconus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201804003284326

Enrollment

200

Registered

2018-04-02

Start date

2014-10-02

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases Surgery Keratoconus

Interventions

CXL 1st then ICRS after 6 months

ICRS 1st then CXL after 6 months

combined ICRS and CXL

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age less than 30 years old Grade 1,2 and 3 Keratoconus No previous interventions Follow up for 3 years

Exclusion criteria

Exclusion criteria: Corneal opacity Previous Hydrops Age more than 30 years

Design outcomes

Primary

Measure	Time frame
Stability and prevention of KC progression	—

Secondary

Measure	Time frame
Corneal flattening and visual improvement	—

Countries

Egypt

Contacts

Public ContactAhmed Tawfik

Professor of ophthalmology, Zagazig University Hospital.

atawfika@gmail.com01000089352

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026