Circulatory System vasoplegic syndrome, coronary artery bypass graft surgery
Conditions
Interventions
terlipressin infusion
Sponsors
Ain Shams University Hospitals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients on angiotensin II receptor antagonist losartan for at least 4 weeks before operation normal or mild impairment of left ventricular function (EF ¿ 40 by transthoracic echocardiography).
Exclusion criteria
Exclusion criteria: Patients with a critical preoperative state were excluded from the study, including patients with intractable ventricular arrhythmias, previous aborted sudden cardiac death, preoperative mechanical ventilation, preoperative use of inotropes, preoperative use of intra-aortic balloon counter-pulsation, recent myocardial infarction. Patients with previous cardiac surgery, associated valvular heart disease, chronic lung disease, extra-cardiac arteriopathy, moderate to severe renal impairment were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of vasoplegic syndrome | — |
Secondary
| Measure | Time frame |
|---|---|
| inotropic score ;vasopressor dependency index ;Hemodynamic parameters: mean arterial blood pressure, central venous pressure, Cardiac index, systemic vascular resistance index. | — |
Countries
Egypt
Contacts
Public ContactMohamed Saleh
Lecturer of anesthesia
Outcome results
None listed