Cancer cancer
Conditions
Interventions
Group I (CPN 20)
Group II (CPN 40)
Sponsors
suez canal university hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Adult patients of either sex 18 years or older. 2.Patients with the diagnosis of histologically proven or radiologically consistent, surgically unresectable upper abdominal malignancies (including gastric, pancreatic, biliary system). 3.Patients with visual analogue scale (VAS) scores of equal to or more than 4/10 due to cancer related visceral pain in spite of adequate medical management (defined as the highest analgesia possible without intolerable side effects using opioid and non-opioid drugs according to the world health organization analgesic step ladder).
Exclusion criteria
Exclusion criteria: 1.Refusal of participation in the study. 2.Patients received celiac or splanchnic blocks previously as a neurolytic management for cancer pain or those who did not respond to the diagnostic anesthetic block. 3.Patients received intrathecal or epidural interventional implantable devices for cancer pain. 4.Patients allergic to local anesthetics used in the diagnostic block. 5.Patients with coagulopathies not correctable with active medical management. 6.Patients with uncontrolled hypotension. 7.Patients suffering from pain not related to the abdominal malignancy such as neuropathic pain or central pain conditions. 8.Patients with documented metastatic lesions in other sites of the body contributing to pain severity. 9.Patients with psychiatric disorders preventing adequate assessment and data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale scores | — |
Secondary
| Measure | Time frame |
|---|---|
| total daily opioid consumption ;quality of life using the general functional assessment of cancer therapy scale (FACT-G);heamodynamics:heart rate , systolic blood pressure , diastolic blood pressure , mean arterial pressures and pulse oximetry saturation ;Complications of the procedure including hypotension, diarrhea, hematoma, infection, procedure related pain, neurologic complications, and mortality | — |
Countries
Egypt
Contacts
Public ContactReda Ismail
lecturer of anesthesia and intensive care
Outcome results
None listed