A randomised double blind placebo controlled study on the effect of intramuscular hyoscine butylbromide and drotaverine in the first stage of active p

A randomised double blind placebo controlled study on the effect of intramuscular hyoscine butylbromide and drotaverine in the first stage of active phase of labour on labour and delivery outcome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201803003208333

Enrollment

Registered

2018-03-18

Start date

2017-01-02

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Active management of Labour

Interventions

HYOSCINE BUTYLBROMIDE

DROTAVERINE HYDROCHLORIDE

Normal saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: singleton pregnancy vertex presentation term pregnancy had no co-existing medical illness had no contraindication to vagina delivery had spontaneous rupture of membrane in labour but not more than 12 hours duration.

Exclusion criteria

Exclusion criteria: parturient who had previous uterine surgeries fetal malpresentation antepartum haemorrhage twin pregnancy chronic medical illness prolonged premature rupture of fetal membranes epidural analgesia in labour parturients with contraindication to vagina delivery

Design outcomes

Primary

Measure	Time frame
Rate of cervical dilatation in the active phase of first stage of labour and Time to full cervical dilatation	—

Secondary

Measure	Time frame
Duration of second and third stage of labour. Potential fetomaternal complications. Labour pain score	—

Countries

Nigeria

Contacts

Public ContactMorakinyo Abiodun Alakaloko

Senior Registrar

morakinyoalakaloko@gmail.com+2348060075255

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026