Effectiveness of a six-week treatment course of vitamin D in steady state sickle cell anaemia children with hypovitaminosis

Comparative Effectiveness of six-week treatment course of vitamin D2 and D3 in children with sickle cell anaemia in steady state: A randomized clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201803003160262

Enrollment

154

Registered

2018-03-03

Start date

2018-03-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haematological Disorders Nutritional, Metabolic, Endocrine Sickle cell anaemia

Interventions

oral vitamin D3

Oral vitamin D2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children with sickle cell anaemia aged 1 to 18 years Children with 25(OH)D level below 75nmol/L Children whose parents give consent Children 7 years and above that assent to be part of the study

Exclusion criteria

Exclusion criteria: Children with established diagnosis of tuberculosis, asthma or on steroid Children with established renal or kidney disease Children on anticonvulsants

Design outcomes

Primary

Measure	Time frame
Mean rise in serum 25(OH)D following 6 weeeks treatment of hypovitaminosis	—

Secondary

Measure	Time frame
Mean rise in serum calcium and alkaline phosphatase following 6 weeks correction of hypovitaminosis	—

Countries

Nigeria

Contacts

Public ContactAdaobi Solarin

Consultant Nephrologist/ Lagos State University Teaching Hospital, Ikeja

asolar234@yahoo.com(+234)08033041915

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026