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Effect of transcranial direct current stimulation combined with constraint-induced movement therapy on cortical reorganization and functional outcome

Effect of transcranial direct current stimulation combined with constraint-induced movement therapy on cortical reorganization and functional outcome in stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201803003148269
Enrollment
40
Registered
2018-02-26
Start date
2015-07-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases stroke

Interventions

constraint induced movement therapy and active bilateral transcranial direct current stimulation
constraint induced movement therapy and sham bihemispheric transcranial direct current stimulation

Sponsors

Cairo university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -ischemic stroke in the territory of the middle cerebral artery at least 6 months prior to enrollment -age ranged from 45 to 60 years old -no previous or subsequent strokes -at least 10 degrees active wrist dorsiflexion and extension of the metacarpophalangeal and interphalangeal joints of the thumb and at least 2 additional digits 10 degrees at enrollment

Exclusion criteria

Exclusion criteria: spasticity of grade 3 or more other neurologic or orthopedic disorders that could influence upper extremity function history of neurosurgery or epilepsy metallic implants within the brain cardiac pacemaker

Design outcomes

Primary

MeasureTime frame
functional abilities of affected upper extremity ;ipsilesional and contralesional cortical excitability using motor evoked potentials

Secondary

MeasureTime frame
correlation between functional improvement and changes in cortical excitability

Countries

Egypt

Contacts

Public ContactAbd aleem Ateya

professor

aaatteya@gmail.com01007098435

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026