Magnesium sulfate versus fentanyl to control pressor and arousal response to intubation

Bispectral index guided attenuation of pressor and arousal response to endotracheal intubation using magnesium sulfate and fentanyl . A doubleblind, randomized, controlled trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201802003104179

Enrollment

Registered

2018-02-16

Start date

2018-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodynamic and arousal response to airway manipulation

Interventions

Group C

Group M

Group F

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Female, Age 20-60yrs, general anesthesia with orotracheal intubation

Exclusion criteria

Exclusion criteria: .Patients with chronic hypertension,heart disease,heart block,arrhythmia. .Renal Failure, heart failure. .On Beta and/or calcium channel blockers or any drug treatment that would affect blood pressure or heart rate. .Suspected difficult intubation. .More than 1 trial at intubation. .Intubation time >20sec

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure at 2 min post intubation.	—

Secondary

Measure	Time frame
Systolic, Diastolic, Mean blood pressure, Heart rate, BIS	—

Countries

Egypt

Contacts

Public ContactAhmed Mohamed

ahmedelbadawy1991@gmail.com+2 01063919246

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026