Comparison of the anaesthetic effects of 4% articaine hydrochloride and 2% lidocaine hydrochloride for maxillary molar extraction: A randomised trial

Comparison of the anaesthetic effects of 4% articaine hydrochloride and 2% lidocaine hydrochloride for maxillary molar extraction: A randomised double blind crossover study.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201802003023333

Enrollment

Registered

2018-01-27

Start date

2015-01-05

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health Compairing two types of local anaesthetic agents on pain control during dental extractions. Anaesthesia

Interventions

Extraction of upper molar tooth using ARTICAINE

Extraction of upper molar tooth using LIDOCAINE

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Patients that require bilateral extraction of corresponding firm maxillary molar teeth. Acute pulpitis Chronic pulpitis. Acute exacerbation of chronic apical periodontitis. Pre-orthodontic extraction. Chronic apical periodontitis. 2 Patients that are between the ages of 18 and 40 years. 3 Patients that require simple, intra-alveolar extraction only. 4 Consenting patients. 5 Fully erupted teeth.

Exclusion criteria

Exclusion criteria: 1 Presence of underlying systemic diseases such as hypertension, diabetes, blood dyscrasias etc. 2 Non consenting patients. 3 Extractions that end in root fracture. 4 Impacted teeth. 5 Presence of inflammatory conditions such as dentoalveolar abscess. 6 Patients on medication that can interfere with local anaesthetic agents such as meperidine, phenytoin, quinidine and cimetidine. 7 Chronic alcoholic patients

Design outcomes

Primary

Measure	Time frame
Effectiveness of anaesthesia is recorded based on patients' score of the level of pain experienced during extraction exercise for each side of jaw and pain level in buccal and palatal gingival sulci 10 minutes after buccal infiltration usin visual analog scale chart recording.;To determine and compare the effectiveness of buccal infiltrations in anaesthesizing palatal nerve during extraction of upper molars. Using both articaine and lidocaine as anaesthetic agents.	—

Measure

Time frame

Effectiveness of anaesthesia is recorded based on patients' score of the level of pain experienced during extraction exercise for each side of jaw and pain level in buccal and palatal gingival sulci 10 minutes after buccal infiltration usin visual analog scale chart recording.;To determine and compare the effectiveness of buccal infiltrations in anaesthesizing palatal nerve during extraction of upper molars. Using both articaine and lidocaine as anaesthetic agents.

—

Secondary

Measure	Time frame
To determine and compare onset of action of articaine with lidocaine during extraction of maxillary molaes;To determine and compare complications of articaine with lidocainne during upper molar extractions	—

Countries

Nigeria

Contacts

Public ContactOladimeji Akadiri

Supervisor

oaakadiri@yahoo.com07038167498

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026