Exercise and Insulin Resistance

Superior Effects of Short-Term High versus Moderate Intensity Training on Insulin Resistance in Overweight and Obese Adults: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201802003021680

Enrollment

150

Registered

2018-01-27

Start date

2016-06-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine Insulin Resistance

Interventions

High Intensity Interval Training (HIIT)

Continuous Moderate Intensity Training (CMIT)

Control (CNT)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Physically inactive (less than 30 minutes of physical activity five days a week) Overweight/obese (BMI ¿ 25 kg/m2)

Exclusion criteria

Exclusion criteria: Smokers (current or chronic) Taking medications that are known to affect body composition and metabolism

Design outcomes

Primary

Measure	Time frame
Insulin resistance (HOMA-IR);Insulin sensitivity (HOMA-IR);Beta cell function (HOMA-beta)	—

Secondary

Measure	Time frame
Body weight (BW);Body fat (BF);Peak aerobic power (VO2peak)	—

Countries

South Africa

Contacts

Public ContactPhindile Nene

Postgraduate Officer: Health Sciences

Nenep1@ukzn.ac.za+27 312608280

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026