Injury, Occupational Diseases, Poisoning Paediatrics Acute kidney injury Kidney Disease
Conditions
Interventions
Conventional peritoneal dialysis
continuous flow peritoneal dialysis
Sponsors
Peter Nourse
Andrew Argent
Mignon McCulloch
Brenda Morrow
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Paediatric patients 1 day to 5 years of age in ICU setting Biochemical criteria of acute kidney injury (AKI): according to the Kidney Injury score (KDIGO) criteria The decision to start acute dialysis will be made based on the biochemical criteria and the clinical opinion of the pediatric nephrologists and the ICU consultants
Exclusion criteria
Exclusion criteria: Clinical condition contraindicates procedure of catheter placement PD. E.g. abdominal wall defects, severe diaphragmatic defects, burns or septic skin lesions covering the whole abdominal wall. Peritonitis only if the catheter is not able to be placed safely.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clearance of : Urea, creatinine, phosphate, potassium, albumin expressed ml/min/1.73 m2 and KT/V(clearance divided by total body water);Total ultra-filtration rate measured in ml/kg per hour | — |
Secondary
| Measure | Time frame |
|---|---|
| Mass transport area co-efficient;glucose absorption;Protein loss in grams;dialysate salt removal;Free water transport ;intraperitoneal pressure;cost comparison between intervention and control;complications | — |
Countries
South Africa
Contacts
Public ContactPeter Nourse
Paediatric Nephrologist, Red Cross War Memorial children's Hospital, University of Cape Town
Outcome results
None listed