Genetic Diseases Mental and Behavioural Disorders Paediatrics epilepsy
Conditions
Interventions
measure serum level of malonaldhyde
auditory P300 event related potential
Sponsors
National Research Center, Giza, Egypt.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: case group: Children with idiopathic epilepsy Aged 6-15 years control group: healthy age and sex matched children
Exclusion criteria
Exclusion criteria: Children with any acute or chronic medical illness Children with mental retardation children with hearing impairment children with any concomitant psychological disorders Children with developmental delay Children with physical disabilities children received any medications affecting cognitive function as antihistamines control group: fullfil the same exclusion criteria and did not have any history of neurological disorders, seizures or family history of epilepsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| assess the association between malonaldhyde level as marker of oxidative stress and selective attention assessed by p300 auditory event related potential in children with idiopathic epilepsy;assess the association between clinical characterestics of epilepsy and the serum level of malonaldhyde oxidative marker and auditory event related potential | — |
Secondary
| Measure | Time frame |
|---|---|
| assess the association between clinical characterestics of epilepsy and the serum level of malonaldhyde oxidative marker and auditory event related potential;assess the impact of proper siezure control on both oxidative stress and selective attention | — |
Countries
Egypt
Contacts
Public ContactMarwa Elhady
lecturer of pediatrics
Outcome results
None listed