HIV/AIDS Paediatrics Early Childhood Development
Conditions
Interventions
None
Early Childhood Developmental Stimulation Box
Sponsors
Empilweni Services and Research Unit (ESRU)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: POC or laboratory-based infant diagnostic test positive on a sample collected within 48 hours of birth, the mother willing and able to provide informed consent.
Exclusion criteria
Exclusion criteria: Expressed intention to leave the Johannesburg area permanently, co-morbidities, birth defects or other conditions which in the opinion of the clinical team have a greater than 50% risk of mortality in the first days of life, active (uncontrolled) maternal psychiatric illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the neurodevelopment of a cohort of early-treated HIV positive children receiving an early childhood stimulation intervention with a cohort of early-treated HIV positive children and HIV-exposed uninfected children not having received the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| To describe the neurodevelopment of a cohort of perinatally-infected HIV positive children initiated on antiretroviral treatment in infancy.;To compare the neurodevelopment of a cohort of early-treated HIV positive children with a control group of HIV-exposed uninfected children;To investigate associations between neurodevelopmental outcomes and environmental factors using the Household Survey and Parenting Stress Index-SF, in early treated perinatally-infected HIV positive children and HIV-exposed uninfected children. | — |
Countries
South Africa
Contacts
Public ContactRenate Strehlau
Deputy Director ESRU
Outcome results
None listed