Esmolol versus Dexmedetomidine for Deliberate Hypotension during Functional Endoscopic Sinus Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201801002878287

Enrollment

Registered

2017-12-15

Start date

2018-01-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Deliberate Hypotension during Functional Endoscopic Sinus Surgery

Interventions

Group E

Group D

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ¿ Adult patients, 20 to 45-year-old, of both genders, scheduled for elective FESS surgery. ¿ American society of anesthesiologists class (ASA) I and II patients.

Exclusion criteria

Exclusion criteria: ¿ Patient refusal. ¿ ASA class III and IV. ¿ Any known hypersensitivity or contraindication to esmolol or dexmedetomidine. ¿ Patients with bleeding diathesis, respiratory problems, liver failure, kidney insufficiency or heart diseases (heart block, or myocardial ischemia). ¿ Patient with poorly controlled arterial hypertension (blood pressure higher than 140/90 mmHg). ¿ Patients planned for redo surgery for recurrent rhinosinusitis. ¿ Patients on anticoagulant, ¿2 agonist or ¿ blocker therapy.

Design outcomes

Primary

Measure	Time frame
¿Total blood loss (ml) during the operation, which is collected by suction added to the estimated from nasal packing.	—

Secondary

Measure	Time frame
¿ Surgeon's satisfaction score with 4 points subjective scale (18) at the end of surgery, as follows:-. ¿ 1 = Bad. ¿ 2 = Moderate. ¿ 3 = Good. ¿ 4 = Excellent.	—

Countries

Egypt

Contacts

Public ContactKhaled Gaballah

Lecturer of Anesthesia and Critical Care Faculty of Medicine, Menoufia University

khgaballah@gmail.com00201016009073

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026