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Different doses of dexmedetomidine for conscious sedation during awake nasotracheal fiberoptic intubation fiberoptic

Comparative study of multiple doses regimen of Dexmedetomidine used for moderate sedation facilitating intubation condition during nasotracheal fiberoptic laryngoscope in awake patients. Randomized prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201712002863123
Enrollment
40
Registered
2017-12-12
Start date
2018-01-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases Surgery patient comfort, intubating condition and hemodynami stability during conscious sedation

Interventions

Group I: patients received I.V. Dexmedetomidine
Group IIpatients received I.V. Dexmedetomidine

Sponsors

Faculty of Medicine, Aswan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients with ASA patients status I and II

Exclusion criteria

Exclusion criteria: Patients with obesity more than 30% above the ideal body weight, patients refusal,gastroesophageal reflux, uncontrolled blood pressure, ischemic heart diseases, diabetic, asthmatic, severe bradycardia or any type of A-V block on ECG,coagulapthy, hepatic, renal dysfunction thrombocytopenia, hyperactive air way diseases, , history of drug maluse,and a long term use of benzodiazepines or antidepressant drugs, any neurological disorders or mental retardation, pregnancy, nasal polyp, history of allergy to any used medication, any apparent airway abnormalities with mallampati score ¿ III(7), thyromental distance ¿ 6 centimeters and history of laryngeal or pharyngeal surgeries all were excluded from our study.

Design outcomes

Primary

MeasureTime frame
The Observer¿s Assessment of Alertness and Sedation Scale (OAA/S) and level of discomfort during nasal fiberoptic intubation

Secondary

MeasureTime frame
). Hemodynamic parameters including Heart Rate (HR), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP), SpO2 and EtCO2 were also detected during preoxygenation, fiberscope insertion (1, 2, 3, 4, 5and 8 min. intervals) and endotracheal intubation(1, 2, 3, 4, 5and 8 min. intervals)

Countries

Egypt

Contacts

Public ContactSherif Arafa

Lecturer of Anesthesia, ICU, Aswan University

sherifarafa1020@gmail.com01005714014

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026