Different additives in peribulbar block

Outcome values of adding sodium bicarbonate,Dexamethasone or fentanyl to local anesthetic in peribulbar block during Vitreoretinal surgeries. A Prospective Randomized Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201712002860265

Enrollment

120

Registered

2017-12-12

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

hyaluronidase in peribulbar block

sodium bicarbonate in peribulbar block

fentanyl in peribulbar block

dexamethasone in peribulbar block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ¿ Age: 40-60 years old. ¿ American society of anesthesiologist physical status (ASA): I-II. ¿ Operation: vitreoretinal surgery

Exclusion criteria

Exclusion criteria: ¿ ASA :III-IV ¿ Uncooperative patient. ¿ Allergy to medication used. ¿ Patient refusal ¿ coagulopathy or history of anticoagulant therapy, ¿ patient with neurological manifestations ¿ failed regional anesthesia ¿ posterior staphyloma, ¿ disturbed conscious level, ¿ active respiratory disease, ¿ poor communication ability as deafness or mute . ¿ patients with excessive tremors or agitations, impaired orbital/periorbital sensations, and patients with glaucoma

Design outcomes

Primary

Measure	Time frame
intraocular pressure, onset and duration of anesthesia and akinesia	—

Secondary

Measure	Time frame
postoperative pain , firest analgesic requirement and side effects	—

Countries

Egypt

Contacts

Public ContactSherif Arafa

Lecturer of Anesthesiology and ICU, Faculy of Medicine, Aswan University

sherifarafa1020@gmail.com01005714014

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026