The utility of remifentanil compared with Nitroglycerin for deliberate hypotensive anaesthesia throughout tympanoplasty. Randomized and Observer-blind

The utility of remifentanil compared with Nitroglycerin for deliberate hypotensive anaesthesia throughout tympanoplasty. Randomized and Observer-blinded clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201712002826324

Enrollment

Registered

2017-11-30

Start date

2016-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear, Nose and Throat deliberate anaesthesia

Interventions

nitroglycerin group (group NTG)

remifentanil group (group REMI)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 60 patients of both genders aged 18 to 60 years with an American Society of Anesthesiologists physical status 1 to 2 who were prepared for tympanoplasty under general anesthesia were enrolled

Exclusion criteria

Exclusion criteria: Exclusive criteria were; patients aged ¿ 18 years, hypersensitivity to the studied drugs, neuropsychiatric disorders, current opioid or substance abuse, kidney, heart, liver diseases, coagulopathy or drugs affecting coagulation.

Design outcomes

Primary

Measure	Time frame
The primary outcome measures were to keep up MAP between 60 and 70 mmHg with ideal vision of operative site	—

Secondary

Measure	Time frame
Surgery time, anesthesia time, deliberate hypotensive anaesthesia times were analyzed. Adverse effects were reported. A four point scale was used for surgeon's satisfaction by the same working surgeon	—

Countries

Egypt

Contacts

Public Contactnagat elshmaa

assistant professor

nagat_elshmaa@yahoo.com00101211865637

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026