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Effect of Increasing The Dose of Nalbuphine As AN Adjuvant To Local Anesthetic In Paravertebral Block In Mastectomies.A Randomised Double Blinded Stud

Effect of Increasing The Dose of Nalbuphine As AN Adjuvant To Local Anesthetic In Paravertebral Block In Mastectomies.A Randomised Double Blinded Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201711002797317
Enrollment
60
Registered
2017-11-23
Start date
2017-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Surgery breast cancer surgeries mastectomies

Interventions

Group(PB) given bubivacaine0.5%
Group(PBN 1) will be given bubivacaine0.5% plus 10 mg nalbuphine in 1ml,
Group(PBN 2)

Sponsors

Fayoum University hospitals
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Sixty )60( patients American Society of Anesthesiologist (ASA) physical status I/II/III females, aged (18-78) years, undergoing breast surgery will be studied.

Exclusion criteria

Exclusion criteria: Exclusion criteria included patients undergoing bilateral breast surgery or breast reconstruction; those having contra-indications for PVB, e.g., patient refusal, infection at injection site, anticoagulant therapy, abnormal coagulation profile, or hypersensitivity to LA; patients on chronic antiemetics or chronic pain medication; pregnant patients; central neuropathy, liver or renal impairment, drug or alcohol abusers, and those with psychiatric illnesses that would interfere with perception and assessment of pain and obese patients with a body mass index (BMI) >30 kg/m2.

Design outcomes

Primary

MeasureTime frame
Primary outcome measure was cumulative IV tramadol consumption over 24 h, pain scores at rest and active movement of ipsilateral arm.

Secondary

MeasureTime frame
Secondary outcome measures will include intraoperative fentanyl requirements, TFR, bradycardia , hypotension, sedation scores, complications ( nausea. vomiting, pruritus), time to mobilize, time to discharge and patient satisfaction.

Countries

Egypt

Contacts

Public ContactAtef Mohamed Sayed

Lecturer of Anesthesiology , Fayoum University, Faculty of medicine

Mygodprotection@yahoo.com002 01016581609

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026