Pre-emptive oral pregablin in postoperative pain after orthopedic lower limb surgeries under spinal anesthesia

The effect of pre-emptive oral pregablin on the control of acute postoperative pain in patients presented for orthopedic lower limb surgeries under spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201711002742202

Enrollment

Registered

2017-11-02

Start date

2017-11-04

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery postoperative pain after orthopedic lower limb surgery

Interventions

Placebo group

Pregablin group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 60 patients, ASA Physical status I&II, 25 -50 years of both sex presented for internal fixation of fracture femur.

Exclusion criteria

Exclusion criteria: ¿ Patients refusal to participate in the study. ¿ Coagulation disorders ¿ Local skin infection at the side of injection ¿ BMI more than 30kg/m2 or less than 18 kg/m2 ¿ Patients receiving non-steroidal anti-inflammatorydrugs, anti-platelets or neuro-active or antipsychotic drugs and patients with history of recurrent hyperacidity or gastritis ¿ History of drug dependency or substance addiction ¿ A known sensitivity to pregabalin, known to be allergic to any medicines

Design outcomes

Primary

Measure	Time frame
the time for the first request for rescue analgesia	—

Secondary

Measure	Time frame
the severity of postoperative pain.	—

Countries

Egypt

Contacts

Public Contactnada Omara

Dr.nada.emera@gmail.com01118342012

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026